What is Calve's Disease?

Description of the disease

Calve's Disease, or Calve's Syndrome, is a rare genetic condition that leads to a disruption in the metabolism of bone tissue.

Classification

• Calve's Disease Type 1
• Calve's Disease Type 2

Symptoms

• Bone pain
• Deformation of the skeleton
• Mild tendency to fractures

Causes

The disease is caused by a mutation in the COL1A1 or COL1A2 genes, which are responsible for the formation of collagen, the main protein of bones.

Diagnosis

The diagnosis is made based on clinical manifestations and genetic tests.

Treatment

Treatment is aimed at improving the patient's quality of life, including the use of pain relievers and physiotherapy.

Prevention

Since the disease is genetic, there are no specific prevention methods, but genetic counseling can help reduce the risk of passing the disease to offspring.

Doctor

Treatment is conducted by an orthopedic surgeon or geneticist.