What are Benign Hyperbilirubinemias?

Description of the disease

Benign hyperbilirubinemias are a group of genetic disorders characterized by elevated levels of bilirubin in the blood, but without pathological changes in the liver or bile ducts.

Classification

• Genetic hyperbilirubinemia type I (Gilbert);
• Genetic hyperbilirubinemia type II (Dubin-Johnson);
• Genetic hyperbilirubinemia type III (Crigler-Najjar).

Symptoms

Usually benign hyperbilirubinemias are asymptomatic, although some patients may occasionally experience weakness, nausea, or discomfort in the abdominal area.

Causes

The cause of benign hyperbilirubinemias is a disruption of bilirubin metabolism in the body, due to a defect in the genes responsible for its processing.

Diagnosis

Diagnosis is based on measuring the level of bilirubin in the blood, as well as genetic testing to identify the specific defect.

Treatment

Benign hyperbilirubinemias do not require specific treatment, but in some cases symptomatic therapy may be needed to alleviate discomfort.

Prevention

Since the disease is genetic, there are no specific preventive measures. It is important to undergo regular medical observation and follow the recommendations of doctors.

Physician

The diagnosis and treatment of benign hyperbilirubinemias is carried out by a gastroenterologist or geneticist.